Who portrays Mrs. Wheeler Wheeler? Which actor assumes the role of Karen Wheeler in the show? Who is the performer behind Karen Wheeler? Karen is brought to life by whom? Who plays the character of Karen the mother on the show? Whom is the talent personifying Karen Wheeler's character to life? What actor takes on the role of Karen Wheeler in the television show? Who acts Karen Mrs. Wheeler? Whom is the talented individual enacting Karen Wheeler on the series? Which actor brings the character of Karen Wheeler to the screen?